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TECHNOLOGY of PHARMACEUTICAL MANUFACTURE (educational
grant)
INTRODUCTION
Technology
Medicinal forms as science.
CHAPTER 1
the History of technology
Medicinal forms
.
CHAPTER 2
Kinds
Pharmaceutical manufacture
.
CHAPTER
3
Base sciences .
Bioafarmation.
Pharmaceutical факторы.
CHAPTER
4
Incompatibility.
Medicinal substances.
Physical and physical and chemical
Incompatibility. Chemical incompatibility.
CHAPTER 5
Auxiliary substances.
Nature
Auxiliary substances. Synthetic and half-syntetic
Auxiliary substances.
CHAPTER
6
Other auxiliary substances
. Form-making substances. Stabilizers.
Antibacterial stabilizers . Prolongators. Korrigents.
CHAPTER
7
Systems of classifications of medicinal forms.
Classification on modular
To a status. substance. the classification based on
A way of application of medicinal forms, it is offered V.A.
Tikhomirov. Dispersologic classification.
CHAPTER 8
Solid medicinal
forms.
Gathers. Powders.
CHAPTER 9
Powder technology .
Crushing.
Features powdering. Mixing. Batching.
Packing powders.
CHAPTER 10
Tablets.
The basic requirements to tablets and theoretical bases of tableting.
Accuracy of batching. Granulating .
Mechanical durability. Splitting.
CHAPTER 11 Technology of tablets.
Mixing.
Granulating.
Damp granulating. Dry granulating.
Pressing-tableting.
Direct pressing. Dedusting.
CHAPTER
12
Basic groups
Auxiliary substances for
tableting. Fillers
. Fluffers. Connecting substances. The substances promoting sliding.
Dyes.
CHAPTER 13
the Covering of tablets
shells.
Film coverings. Water-soluble coverings.
Coverings, soluble in gastric соке. Coverings,
Soluble in intestines. Insoluble coverings.
CHAPTER 14
Methods of drawings
Film coverings.
Napressovannye coverings.
Trituratsionnye tablets.
CHAPTER 15
Prospectives developments
Technologies tablets.
Pressing coverings.
Trituratsionnye tablets.
CHAPTER 16
Dragees.
Granules.
CHAPTER
17
Soft medicinal
forms. Requirements to ointments. Classification of bases for ointments.
Technology of ointments. Introduction of medicinal substances in ointments.
The basic directions of perfection of quality and
Technologies ointments.
CHAPTER 18
Gelatine capsules.
Firm capsules. Soft capsules . Reception
Gelatin. Reception of soft gelatinous capsules. Preparation gelatinous
solution. Manufacturing of shells of capsules by way of dipping.
Filling capsules. Other ways of reception of gelatinous shells.
CHAPTER 19
Microcapsules.
Mikrokapsulating.
Application of microcapsules.
Technology of microcapsulation.
CHAPTER 20
Rectal
Medicinal forms.
Suppozitorii. Technology suppozitoriev. Formation and
Packing candles. Prospects of development rectal
LF.
CHAPTER
21
Eye medicinal forms.
Maintenance of chemical stability. Maintenance
Absence of mechanical inclusions. Maintenance
Comforts. Technology of eye drops. Eye ointments.
Eye film.
CHAPTER
22
Aseptics and sterility.
Aseptic
Conditions . Sources of pollution injective solutions.
The requirements showed to injective solutions.
CHAPTER 23
Technology
injective preparations.
the Description of the technological circuit of the manufacture realizing vacuum
technology.
Clearing solutions.
CHAPTER 24
Solvents and
ekstragenty.
Etyl spirit. WATER.
Water distilled (Aqua destillata). Water
demineralized.
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